Tumor-specific transplantation antigens in spontaneously transformed hamster cell lines
نویسندگان
چکیده
منابع مشابه
Myeloma proteins as tumor-specific transplantation antigens.
BALB/c mice immunized with myeloma proteins 315 or 460 made antibodies to the individually specific ("idiotypic") determinants of these proteins and suppressed growth of the corresponding transplanted tumor cells (MOPC-315 or MOPC-460). Stable, variant MOPC-315 tumors that produce only the light chain of protein 315 grew in several of the mice immunized with this protein, probably because the a...
متن کاملCytogenetic profile of in vitro spontaneously transformed and chemical tumor-derived cell lines related to the mouse lung alveologenic carcinoma.
The karyotypes for a unique series of cloned untransformed and spontaneously and urethan-transformed mouse lung alveologenic carcinoma cell lines were compared by G-banding. All cell lines exhibited altered chromosome number accompanied by chromosomal aberrations. Both spontaneously and chemically transformed lines contained a higher proportion of cells carrying double minutes, short-arm chromo...
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1 Presented at the 58th Annual Meeting of the American Asso ciation for Cancer Research, April 1967, Chicago, Illinois. The work of the author and his associates was supported by grants from the Swedish Cancer Society, the Medical Research Council, by Grants CA-04747 and CA-03700 from the National Cancer In stitute, USPHS, from the Damon Runyon Memorial Fund (DRG598), the Jane Coffin Childs Mem...
متن کاملTumor-specific transplantation antigens in reticulum cell sarcomas and lymphomas induced by the friend virus complex.
The reticulum cell sarcomas induced by Friend leukemia virus (FLV) and the lymphomas induced by the Friend virus-associated lymphatic leukemia virus (LLV) have been investigated for both their antigenic relationships and the presence in them of common tumor-specific transplantation antigens. Since noninfectious reticulum cell sarcomas contain ing the Friend virus genome were available, this was...
متن کاملInduction of apoptosis in human tumor cell lines by platelets
Introduction: It has been reported that platelets can eradicate tumor cells in vitro, although the mechanism of this effect has not been determined. The effect of platelets on the induction of apoptosis in tumor cells is largely unknown. Materials and methods: To investigate this effect, two human hematologic cell lines, K562 and Daudi, were independently faced with unstimulated and thromb...
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ژورنال
عنوان ژورنال: Cancer
سال: 1977
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(197704)39:4<1450::aid-cncr2820390416>3.0.co;2-h